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Even while on hemophilia A treatment

Breakthrough Bleeds can Still Happen

What role do coagulation markers, like thrombin generation, play in bleed protection?

Learn more

David, an adult man living with hemophilia A, rides his bicycle.

Strong, Stable Clots Rely on Thrombin

Thrombin helps form fibrin, a protein that acts like a mesh to hold a clot together.

When the body doesn’t make enough thrombin, bleeding may occur more frequently or severely^a

^aIn a study that evaluated 106 people with rare inherited bleeding disorders across 6 Dutch hemophilia treatment centers, insufficient thrombin generation was associated with more severe bleeding.

LEARN MORE ABOUT BLEED PROTECTION

		What is thrombin, and why is it important?
		What are the factors that may contribute to bleeds, even on prophylaxis?
		Resources to help you talk with your care team about your bleed protection.

Visit SpeakYourHemTruth.com

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